CD43 anticorps

N° du produit ABIN6297681

Cet anticorps anti-CD43 est un anticorps Souris Monoclonal détectant CD43 dans IHC. Adapté pour Humain.

Aperçu rapide pour CD43 anticorps (ABIN6297681)

Antigène: CD43 (SPN) (Sialophorin (SPN))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD43 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-CD43 anticorps

Fonction: Mouse anti-Human CD43 Antibody [IHC only]

Specificité: Cell surface

Purification: Stimulated human leukocytes were used as the immunogen for the CD43 antibody.

Immunogène: Stimulated human leukocytes were used as the immunogen for the CD43 antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD43

Antigène: CD43 (SPN) (Sialophorin (SPN))

Autre désignation: Leukosialin

Sujet:

Target Description: It recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop III). 70-90 % of T-cell lymphomas and from 22-37 % of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Gene Symbol: SPN///CD43

ID gène: 6693

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity